
The Preferred Fuel
Here’s another point where inverting the usual framing is more helpful than the standard narrative. Let’s frame it around the question: “Which fuel does the body actually prefer?”
The Usual Message
Heard in a nutrition documentary (1):
In carbohydrate metabolism, the body uses glucose, its most important energy source. Excess glucose is also stored as fat. When glucose runs short, the body switches to fat metabolism and taps into its fat reserves so that our cells can keep working.
And in the DGE Fat Guideline (2), fat metabolism (ketosis ) is described as a metabolic imbalance or - in the german version - derailment:
At the same time, biomarkers for the supply of essential nutrients and metabolic imbalances (e.g. ketone bodies) must be observed.
Does That Already Answer the Question?
Both statements sound as though the body burns carbohydrates first, and only then fat. That’s true - but it easily creates the impression that carbohydrates are preferred, and therefore need to be replenished to avoid slipping into emergency mode, the “derailment”.
I’ll take my usual approach of reversing cause and effect. To illustrate, let me bring in another fuel that doesn’t usually feature in this discussion: alcohol.
Alcohol is a toxin. It can be burned (alcohol is not calorie-free). When alcohol is present, it is metabolised preferentially - but naturally not because the body prefers this toxin. It has to be broken down as quickly as possible.
Only then does the body turn its full attention back to carbohydrates. And carbohydrates, much like alcohol, are not entirely harmless: we know chronically elevated blood sugar as diabetes (though there are other lenses on that too - more in a later article), and it is not healthy. The more sugar available, the more AGEs can form in the body.
Only when blood sugar is low enough that it can no longer cause significant damage does the body turn to fat. Sugar is therefore not the preferred fuel - it’s the one that causes more damage when in excess.
The Answer
The preferred fuel for nearly all cells in our body (3) is fat. The body simply prefers to deal with toxins first, before returning to normal operations.
Example: a very lean person weighing 80 kg with 10% body fat has 8 kg of fat stored - around 56,000 kcal (4). Carbohydrates account for roughly 2,000 kcal. That’s hardly a convincing argument for a preference…

It does no good to give overweight people the constant impression that fat-burning is the body’s emergency mode: it is the default. It’s just a mode that becomes hard to reach with excessive carbohydrate intake and constant snacking.
Try it in the Simulator on this site
But the Experts Say…
Let me return to the DGE quote above to close, because it takes some nerve as a nutrition nerd to question a professional society…
The only explanation I can think of is that someone confused “ketosis” (a normal metabolic state in which the body primarily burns fat) with ketoacidosis - which could genuinely be called a metabolic imbalance or even derailment.
If ketosis were a derailment, I would by now have been living with a derailed metabolism for nearly 14 years - in which case I’d be curious to know when the adverse effects are typically supposed to kick in.










